Brain Health Study

The Brain Health Study, under the direction of Drs. Dean and Ayesha Sherzai, is examining the impact of lifestyle on maintaining brain health and preventing dementia and other neurological diseases. The study requires ongoing participation in the Healthy World Vitality Plan and/or the Sherzais’ Brain Health Revolution subscription program, as well as annual completion of lifestyle questionnaires, a short cognitive assessment and sharing annual lab results with the Sherzais.

To ensure validity of study results, participants must meet certain qualifying criteria. Please use the checklist below to determine if there are any factors that would disqualify you from the study.

Brain Health Study Disqualifying Factors:

  • Younger than 55.
  • Not fluent in English.
  • Not available or not committed to continued participation in Vitality Group meetings.
  • Significant, uncorrected vision or hearing loss that would impair your ability to participate in the group or read documents.
  • Currently enrolled in other studies.
  • Currently on hospice.
  • Diagnosed with dementia by a doctor (Alzheimer’s, frontotemporal, or another form of dementia).
  • Having difficulty with daily activities to the extent that you can’t do some driving, cooking, take care of your finances or your medications.
  • Diagnosed with any significant neurological disease (Dementia, Parkinson’s, Huntington’s, normal pressure hydrocephalus, brain tumor, progressive supranuclear palsy, seizure disorder, subdural hematoma with residual cognitive impairment, multiple sclerosis, history of significant head trauma or known structural brain abnormalities).
  • Currently have cancer, or have been diagnosed and treated with chemo/radiation in the last 3 years (except for basal cell or squamous cell skin cancer, stable prostate cancer or cervical cancer, which are not disqualifying).
  • Have experienced clinical depression in the last year. (Note: Everyone feels “blue” or “down” from time to time. What we’re talking about is a persistent feeling of hopelessness, feeling “down” or other depression symptoms for two weeks or longer. Depression controlled by medications is okay, except for those tricyclic antidepressants which are disqualifying.)
  • Have taken any of the following medications in the last three months:
    • Tricyclic antidepressants
    • Antipsychotics (e.g. Haldol)
    • Mood-stabilizing psychotropic agents (e.g. Lithium)
    • Psychostimulants
    • Opiate analgesics
    • Antiparkinsonian medications
    • Medications to control seizures (anticonvulsant medications)
    • Corticosteroids
    • Medications with significant central anticholinergic activity
  • Currently taking coumadin.
  • Have had or currently have the following significant health concerns:
    • Class III or IV congestive heart failure
    • Clinically significant aortic stenosis
    • History of cardiac arrest
    • Uncontrolled angina
    • Lung disease requiring oxygen
    • Renal (kidney) disease requiring dialysis treatments
    • Major stroke in the past two years
    • In the last 6 months, myocardial infarction
    • In the last 6 months, major heart surgery (Includes valve replacement, bypass surgery, stent placement, angioplasty)
    • In the last six months, Deep Vein Thrombosis (blood clots)
    • In the last six months pulmonary embolus (blood clots in the lung)
  • Have a BMI greater than 40 (For help calculating your BMI, click this link:

If none of the above factors apply to you, then you are qualified to complete the consent process and take a brief cognitive assessment.  We will send you an electronic consent form for your signature, and your coach will complete the cognitive assessment as part of his or her initial Zoom call with you.  If you have questions about any aspects of the consent form or process, please contact us at, or 928-821-6754 or 928-821-5888.